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The top hotels in Cairo, USA

We ranked the top hotels in Cairo, Illinois, USA based on an unbiased analysis of awards, expert recommendations, and user ratings.

18 guest reviews

Stay near the banks of the Ohio and Mississippi rivers at the Quality Inn hotel in Cairo, Illinois. The hotel's location off Interstate 57 provides convenient access to Fort Defiance State Park, Wickliffe Mounds State Park, Magnolia Manor, Birds Blue...